Week 10 NFL odds, lines, best bets, predictions: Computer model likes Buccaneers and 49ers

SportsLine’s advanced model has locked in its NFL bets today from 10,000 simulations

Familiar matchups abound on the NFL Week 10 schedule as there are half a dozen divisional games you can make Week 10 NFL picks on. The highlight of that slate is Rams vs. 49ers, which has L.A. as 3.5-point road favorites, per the latest NFL odds. The Niners won, 26-23, when the two met in early October, but the Rams had won the three prior matchups. This is one of four games with a Week 10 NFL spread that favors the road team.

Other divisional contests include Bills vs. Dolphins (+8.5), Texans vs. Jaguars (+1.5) and Saints vs. Panthers (-4.5). The entire NFC West will do battle as Seahawks vs. Cardinals has Seattle favored by 6.5 points, per the Week 10 NFL lines, with both teams coming off primetime games. The non-divisional slate is highlighted by Steelers vs. Chargers (-3) on Sunday night and Eagles vs. Packers (-2.5) on Monday night.

All of the updated Week 10 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 10 NFL picks now

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The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated

since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its

and NFL betting lines and locked in betting picks for every NFL matchup.

Read the full article at: CBS Sports